Human CLDN5(Claudin 5) ELISA Kit

Human CLDN5(Claudin 5) ELISA Kit

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Rat Claudin 5 (CLDN5) ELISA Kit
RD-CLDN5-Ra-48Tests	Reddot Biotech	48 Tests	EUR 557

Rat Claudin 5 (CLDN5) ELISA Kit
RD-CLDN5-Ra-96Tests	Reddot Biotech	96 Tests	EUR 775

Mouse Claudin 5 (CLDN5) ELISA Kit
DLR-CLDN5-Mu-48T	DL Develop	48T	EUR 527
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Claudin 5 (CLDN5) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Claudin 5 (CLDN5) ELISA Kit
DLR-CLDN5-Mu-96T	DL Develop	96T	EUR 688
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Claudin 5 (CLDN5) in samples from tissue homogenates, cell lysates or other biological fluids.

Rat Claudin 5 (CLDN5) ELISA Kit
DLR-CLDN5-Ra-48T	DL Develop	48T	EUR 549
Description: A sandwich quantitative ELISA assay kit for detection of Rat Claudin 5 (CLDN5) in samples from tissue homogenates, cell lysates or other biological fluids.

Rat Claudin 5 (CLDN5) ELISA Kit
DLR-CLDN5-Ra-96T	DL Develop	96T	EUR 718
Description: A sandwich quantitative ELISA assay kit for detection of Rat Claudin 5 (CLDN5) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Claudin 5 (CLDN5) ELISA Kit
RDR-CLDN5-Mu-48Tests	Reddot Biotech	48 Tests	EUR 557

Mouse Claudin 5 (CLDN5) ELISA Kit
RDR-CLDN5-Mu-96Tests	Reddot Biotech	96 Tests	EUR 774

Rat Claudin 5 (CLDN5) ELISA Kit
RDR-CLDN5-Ra-48Tests	Reddot Biotech	48 Tests	EUR 583

Rat Claudin 5 (CLDN5) ELISA Kit
RDR-CLDN5-Ra-96Tests	Reddot Biotech	96 Tests	EUR 811

Claudin 5 (CLDN5) ELISA Kit
abx595128-96tests	Abbexa	96 tests	EUR 637

Human Claudin 5 (CLDN5) ELISA Kit
SEF295Hu-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	EUR 4731.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Claudin 5 (CLDN5) in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Human Claudin 5 (CLDN5) ELISA Kit
SEF295Hu-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	EUR 477.3
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Claudin 5 (CLDN5) in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Human Claudin 5 (CLDN5) ELISA Kit
SEF295Hu-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	EUR 639
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Claudin 5 (CLDN5) in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Human Claudin 5 (CLDN5) ELISA Kit
SEF295Hu-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	EUR 2575.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Claudin 5 (CLDN5) in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Human Claudin 5 (CLDN5) ELISA Kit
4-SEF295Hu	Cloud-Clone	EUR 4782.00 EUR 2526.00 EUR 640.00	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Claudin 5 (CLDN5) in samples from serum, plasma, tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Claudin-5(CLDN5) ELISA kit
CSB-EL005507HU-24T	Cusabio	1 plate of 24 wells	EUR 165
Description: Quantitativesandwich ELISA kit for measuring Human Claudin-5 (CLDN5) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Claudin-5(CLDN5) ELISA kit
1-CSB-EL005507HU	Cusabio	EUR 804.00 EUR 5099.00 EUR 2704.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Claudin-5(CLDN5) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Claudin 5 (CLDN5)ELISA kit
201-12-2304	SunredBio	96 tests	EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Claudin 5 (CLDN5) ELISA Kit
20-abx151085	Abbexa	EUR 7378.00 EUR 3933.00 EUR 911.00	10 × 96 tests 5 × 96 tests 96 tests

Human Claudin 5 (CLDN5) ELISA Kit
abx252223-96tests	Abbexa	96 tests	EUR 707

Human Claudin 5 ELISA Kit (CLDN5)
RK01129	Abclonal	96 Tests	EUR 521

Human Claudin 5(CLDN5)ELISA Kit
QY-E03551	Qayee Biotechnology	96T	EUR 361

Human CLDN5(Claudin 5) ELISA Kit
EH2839	FN Test	96T	EUR 524.1
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human Claudin- 5, CLDN5 ELISA KIT
ELI-10828h	Lifescience Market	96 Tests	EUR 824

Human Claudin 5(CLDN5) ELISA kit
E01C0988-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Human Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Claudin 5(CLDN5) ELISA kit
E01C0988-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Human Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Claudin 5(CLDN5) ELISA kit
E01C0988-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Human Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Claudin 5 (CLDN5) ELISA Kit
SEF295Mu-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	EUR 4862.4
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Claudin 5 (CLDN5) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Claudin 5 (CLDN5) ELISA Kit
SEF295Mu-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	EUR 488.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Claudin 5 (CLDN5) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Claudin 5 (CLDN5) ELISA Kit
SEF295Mu-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	EUR 654.4
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Claudin 5 (CLDN5) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Claudin 5 (CLDN5) ELISA Kit
SEF295Mu-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	EUR 2644.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Claudin 5 (CLDN5) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Claudin 5 (CLDN5) ELISA Kit
4-SEF295Mu	Cloud-Clone	EUR 4913.00 EUR 2595.00 EUR 655.00	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Claudin 5 (CLDN5) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Rat Claudin 5 (CLDN5) ELISA Kit
SEF295Ra-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	EUR 5124.2
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Claudin 5 (CLDN5) in tissue homogenates, cell lysates and other biological fluids.

Rat Claudin 5 (CLDN5) ELISA Kit
SEF295Ra-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	EUR 509.64
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Claudin 5 (CLDN5) in tissue homogenates, cell lysates and other biological fluids.

Rat Claudin 5 (CLDN5) ELISA Kit
SEF295Ra-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	EUR 685.2
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Claudin 5 (CLDN5) in tissue homogenates, cell lysates and other biological fluids.

Rat Claudin 5 (CLDN5) ELISA Kit
SEF295Ra-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	EUR 2783.4
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Claudin 5 (CLDN5) in tissue homogenates, cell lysates and other biological fluids.

Rat Claudin 5 (CLDN5) ELISA Kit
4-SEF295Ra	Cloud-Clone	EUR 5175.00 EUR 2734.00 EUR 686.00	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Claudin 5 (CLDN5) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Claudin-5(CLDN5) ELISA kit
CSB-EL005507MO-24T	Cusabio	1 plate of 24 wells	EUR 165
Description: Quantitativesandwich ELISA kit for measuring Mouse Claudin-5 (CLDN5) in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Claudin-5(CLDN5) ELISA kit
1-CSB-EL005507MO	Cusabio	EUR 804.00 EUR 5099.00 EUR 2704.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Claudin-5(CLDN5) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Claudin 5 ELISA Kit (CLDN5)
RK02690	Abclonal	96 Tests	EUR 521

Rat Claudin 5 ELISA Kit (CLDN5)
RK03572	Abclonal	96 Tests	EUR 521

Mouse Claudin 5 (CLDN5) ELISA Kit
20-abx153832	Abbexa	EUR 7378.00 EUR 3933.00 EUR 911.00	10 × 96 tests 5 × 96 tests 96 tests

Rat Claudin 5 (CLDN5) ELISA Kit
20-abx155352	Abbexa	EUR 7237.00 EUR 3855.00 EUR 895.00	10 × 96 tests 5 × 96 tests 96 tests

Rat Claudin 5 (CLDN5) ELISA Kit
abx256812-96tests	Abbexa	96 tests	EUR 754

Pig Claudin 5 (CLDN5) ELISA Kit
abx257361-96tests	Abbexa	96 tests	EUR 825

Monkey Claudin 5 (CLDN5) ELISA Kit
abx257873-96tests	Abbexa	96 tests	EUR 981

Rat CLDN5(Claudin-5) ELISA Kit
ER0844	FN Test	96T	EUR 524.1
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 0.094 ng/ml

Rat Claudin 5(CLDN5)ELISA kit
QY-E10357	Qayee Biotechnology	96T	EUR 361

Mouse Claudin 5(CLDN5)ELISA kit
QY-E20335	Qayee Biotechnology	96T	EUR 361

Monkey CLDN5(Claudin 5) ELISA Kit
EMK0113	FN Test	96T	EUR 567.6
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Ape;Sensitivity: 0.094 ng/ml

Mouse Claudin- 5, Cldn5 ELISA KIT
ELI-50506m	Lifescience Market	96 Tests	EUR 865

Bovine Claudin- 5, CLDN5 ELISA KIT
ELI-10604b	Lifescience Market	96 Tests	EUR 928

Rat Claudin 5(CLDN5) ELISA kit
E02C0988-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Rat Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Claudin 5(CLDN5) ELISA kit
E02C0988-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Claudin 5(CLDN5) ELISA kit
E02C0988-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Rat Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Claudin 5(CLDN5) ELISA kit
E03C0988-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Mouse Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Claudin 5(CLDN5) ELISA kit
E03C0988-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Mouse Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Claudin 5(CLDN5) ELISA kit
E03C0988-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Mouse Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Claudin 5(CLDN5) ELISA kit
E07C0988-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Porcine Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Claudin 5(CLDN5) ELISA kit
E07C0988-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Porcine Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Claudin 5(CLDN5) ELISA kit
E07C0988-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Porcine Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Claudin 5(CLDN5) ELISA kit
E06C0988-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Goat Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Claudin 5(CLDN5) ELISA kit
E06C0988-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Goat Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Claudin 5(CLDN5) ELISA kit
E06C0988-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Goat Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Claudin 5(CLDN5) ELISA kit
E04C0988-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Rabbit Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Claudin 5(CLDN5) ELISA kit
E04C0988-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Rabbit Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Claudin 5(CLDN5) ELISA kit
E04C0988-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Rabbit Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Claudin 5(CLDN5) ELISA kit
E08C0988-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Canine Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Claudin 5(CLDN5) ELISA kit
E08C0988-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Canine Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Claudin 5(CLDN5) ELISA kit
E08C0988-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Canine Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Claudin 5(CLDN5) ELISA kit
E09C0988-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Monkey Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Claudin 5(CLDN5) ELISA kit
E09C0988-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Monkey Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Claudin 5(CLDN5) ELISA kit
E09C0988-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Monkey Claudin 5(CLDN5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Claudin 5 (CLDN5) Antibody
20-abx125681	Abbexa	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul

Claudin 5 (CLDN5) Antibody
20-abx008624	Abbexa	EUR 300.00 EUR 439.00 EUR 189.00	100 ul 200 ul 30 ul

Claudin 5 (CLDN5) Antibody
abx010574-100ug	Abbexa	100 ug	EUR 425

Claudin 5 (CLDN5) Antibody
20-abx013036	Abbexa	EUR 314.00 EUR 98.00 EUR 398.00 EUR 495.00	100 ug 10 ug 200 ug 300 µg

Claudin 5 (CLDN5) Antibody
20-abx213665	Abbexa	EUR 411.00 EUR 300.00	100 ul 50 ul

Claudin 5 (CLDN5) Antibody
20-abx213930	Abbexa	EUR 411.00 EUR 300.00	100 ul 50 ul

Claudin 5 (CLDN5) Antibody
20-abx175890	Abbexa	EUR 425.00 EUR 133.00 EUR 1205.00 EUR 578.00 EUR 328.00	100 ug 10 ug 1 mg 200 ug 50 ug

Claudin 5 (CLDN5) Antibody
20-abx175891	Abbexa	EUR 1233.00 EUR 592.00	1 mg 200 ug

Claudin 5 (CLDN5) Antibody
20-abx175892	Abbexa	EUR 1233.00 EUR 592.00	1 mg 200 ug

Claudin 5 (CLDN5) Antibody
20-abx175893	Abbexa	EUR 1302.00 EUR 620.00	1 mg 200 ug

Claudin 5 (CLDN5) Antibody
20-abx171768	Abbexa	EUR 857.00 EUR 439.00	1 mg 200 ug

Claudin 5 (CLDN5) Antibody
20-abx171769	Abbexa	EUR 913.00 EUR 467.00	1 mg 200 ug

Claudin 5 (CLDN5) Antibody
20-abx329518	Abbexa	EUR 314.00 EUR 244.00	100 ug 50 ug

Claudin 5 (CLDN5) Antibody
abx332230-100ul	Abbexa	100 ul	EUR 425

Claudin 5 (CLDN5) Antibody
abx332414-100ul	Abbexa	100 ul	EUR 425

Claudin 5 (CLDN5) Antibody
20-abx326617	Abbexa	EUR 314.00 EUR 244.00	100 ug 50 ug

Claudin 5 (CLDN5) Antibody
20-abx333832	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

ELISA kit for Human CLDN5 (Claudin 5)
E-EL-H1630	Elabscience Biotech	1 plate of 96 wells	EUR 534
Description: A sandwich ELISA kit for quantitative measurement of Human CLDN5 (Claudin 5) in samples from Serum, Plasma, Cell supernatant

Human CLDN5(Claudin 5) ELISA Kit